In Vivo Evidence for Platelet-Induced Physiological Angiogenesis by a COX Driven Mechanism
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چکیده
منابع مشابه
In Vivo Evidence for Platelet-Induced Physiological Angiogenesis by a COX Driven Mechanism
We sought to determine a role for platelets in in vivo angiogenesis, quantified by changes in the capillary to fibre ratio (C:F) of mouse skeletal muscle, utilising two distinct forms of capillary growth to identify differential effects. Capillary sprouting was induced by muscle overload, and longitudinal splitting by chronic hyperaemia. Platelet depletion was achieved by anti-GPIbα antibody tr...
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متن کاملtime course of neuroprotection induced by in vivo normobaric hyperoxia preconditioning and angiogenesis factors
objective(s):every year, a large number of people lose their lives due to stroke. stroke is the second leading cause of death worldwide. surprisingly, recent studies have shown that preconditioning with hyperoxia (ho) increases tissue tolerance to ischemia, ultimately reducing damages caused by stroke. addressed in this study are beneficial contributions from ho preconditioning into reduced har...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0107503